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Evolution is great at solving problems. It's the methods that concern me.
Tim Digger -
Helium, because I'm worth it.
Waterboarding at Guantanamo Bay sounded like a radical holiday opportunity until I looked it up.Comment
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Last edited by Tim Digger; 12-08-2020, 06:27 PM.Evolution is great at solving problems. It's the methods that concern me.
Tim DiggerComment
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My Mother had too much morphine in hospital and it seemed to make her aggressively mad. I did enjoy being favourite child for the afternoon though.Definitely don't doubt Dawn - not if you value your lifeComment
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Tim is probably better placed to answer than me - it’s probably 15+ years since I last prescribed it, as part of the then-bundle for acute severe pulmonary oedema due to heart-failure. These days I tend not to have much to do with such patients; they are generally unfit for anaesthesia, thus I don’t get to operate on them...Comment
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It is probably as much about fashion and fear and reputation as about logic and best drug for the job.
Diamorphine is Diacetyl morphine, Morphine the parent naturally occurring constituent of opium is chemically altered by a relatively simple process in a way which makes it more lipid soluable, but it is actually inactive until it is de acetylated. This turns it into active monoacetyl morphine this deacetylation can take place in most tissues in a body. By many routes (oral or intramuscular injection) there is little if any difference between morphine and diamorphine as both enter the bloodstream and the brain slowly and levels rise slowly, given intravenously diamorphine acts significantly more quickly as the increased fat solubility allows the high blood concentration to pass into the brain faster where it is deacetylated. This produces the "Rush" a desired effect for some non medical purposes!
Also morphine given IV has to be given slowly as it causes the body to release histamine causing an increase in pulse rate which is bad in the circumstances of a heart attack, hence the use of diamorphine described by Ian.
Diamorphine is a white powder and is disolved in water or saline before use, morphine is in sterile liquid solution.
There are other specialist uses and I could probably write an hours lecture on the subject. So I will stop, the fact is it is a better drug that is limited by it's past history and reputation and is hence illegal in many countries even for medical use.Evolution is great at solving problems. It's the methods that concern me.
Tim DiggerComment
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So ...... ..... we have quite a crop of large poppy heads in the garden now the flowers have gone. Hmmmmmm."...are we human, or are we diver?"Comment
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A close call. Nearly sent this text message to my 80 yr old mum:-
" spent most of the day in the shade trying to drink as much fluid as pissible"
Can't edit texts once they're gone."...are we human, or are we diver?"Comment
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Mine would have screamed and run away from the magic box with the daemon in it. She wouldn't even answer a landline.Definitely don't doubt Dawn - not if you value your lifeComment
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At least it's a response.
Mine thought that anything more high-tech than a TV was just 'something other people do'.
My mother-in-law was worse
One of her sons had to teach her how to write a cheque after her husband died.
My father, on the other hand, when confronted with something new first responded with
"what does it do?"
then
"show me."
then
"let me try"
a truly wonderful example to grow up with. The amount of trouble that attitude has got me
into over the years is staggering.Helium, because I'm worth it.
Waterboarding at Guantanamo Bay sounded like a radical holiday opportunity until I looked it up.Comment
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